道一提供核酸药物的一体化递送设计服务（RNA-ADD）。客户带来 RNA 货物与目标组织，我们交付脂质材料、LNP 处方与完整的体内外验证证据 —— 并以现货工具、服务、管线三层结构把「递送能力」变成可持续的生意。
Harmony Tao provides integrated delivery design services for nucleic acid drugs (RNA-ADD). Customers bring the RNA cargo and the target tissue; we deliver lipid materials, LNP formulations and full in vitro / in vivo evidence — turning delivery capability into a sustainable business through three layers: reagent product, services and pipeline.
标准化现货产品，替代 Lipo-fectamine 3000 与进口体内转染试剂的高门槛方案。低单价、可复购、易触达，是最前端的客户入口与现金流。
A standardised off-the-shelf product replacing the high-threshold Lipo-fectamine 3000 and imported in vivo reagents. Low unit price, repeat purchase, easy reach — the front door to customers and to cash flow.
Off-the-shelf · repeat purchase · customer entry以平台四项资产为客户做定制递送设计：脂质材料选型或定制合成、LNP 处方筛选与理化表征、体内外转染验证、动物药效评价。按项目收费，收入体量大、客户黏性高。
Custom delivery design using the four platform assets: lipid selection or custom synthesis, LNP formulation screening and characterisation, in vitro / in vivo transfection validation, animal efficacy evaluation. Project-based fees, larger tickets, stickier customers.
Custom · project-based · data accumulationHT001（肝靶向基因编辑）与 HT002（脾靶向 in vivo CAR-T）由自有平台孵化，走联合开发或许可授权。这是长期价值出口，也是平台能力的最强证明。
HT001 (liver-targeted gene editing) and HT002 (spleen-targeted in vivo CAR-T) are incubated on the platform and advanced through co-development or licensing. This is the long-term value outlet and the strongest proof of platform capability.
Licensing · co-development · high value从 Lipid 分子库与 Ligand 结构库中匹配靶组织，或按需定制合成。
Match the target tissue from the lipid and ligand libraries, or synthesise to order.
粒径、分散度、表面电位、包封率等参数表征，形成可复现处方。
Size, dispersity, surface charge and encapsulation efficiency — a reproducible formulation.
以 Lipoeasy® 工具快速完成细胞层面与动物层面递送验证。
Rapid delivery validation at cell and animal level using the Lipoeasy® tool.
在目标适应症模型上评价递送方案的实际药效表现。
Evaluating real efficacy of the delivery scheme in the target indication model.
用体内外预测模型缩小候选范围，减少试错轮次。
In vitro / in vivo models narrow the candidate space and cut trial-and-error rounds.
适用于已有 RNA 货物、需要解决靶向或安全性问题的团队。
For teams that already have the RNA cargo and need targeting or safety solved.
采购 Lipoeasy® 现货试剂，或按转染需求定制规格与批量。
Buy off-the-shelf Lipoeasy®, or customise spec and bulk for your transfection needs.
围绕 HT001、HT002 及新靶组织方向开展联合开发或授权合作。
Co-development or licensing around HT001, HT002 and new target-tissue directions.
把货物类型、目标组织和当前阶段告诉我们，我们会给出具体的递送路线建议。
Give us the cargo, the target tissue and your stage — we will propose a concrete delivery route.
